Uwe Wittwer's works have been exhibited internationally since the mid-1980s. Past solo exhibitions include: The Mission, Parafin, London (2022), Schwarzer Schnee, Judin, Berlin, Holzhacker.Spiegel, Galerie Peter Kilchmann, Zurich; Settings of Wrath, at the Musée Ariana in Geneva (all 2021); The Black Suns, Grenchen Art Museum (2019); The Spoils of Ward, Judin, Berlin and Shelter, Galerie Parafin, London (2018).
Important group exhibitions took place in the following institutions, among others: Gewerbemuseum Winterthur, Winterthur (2023); Szydlowksi Gallery, Warsaw (2023); Centre PasquArt, Biel (2022), Parafin, London (2022), Kunstmuseum Solothurn (2021); Kunstmuseum Bern (2019); Herbert Art Museum, Coventry (2018); Langmatt Museum, Baden (2017); Abbot Hall Art Gallery, Kendal (2013); Kunstmuseum Solothurn (2013); Tate Britain, London (2011); PS1 MoMa, New York (2006). Wittwer's works are in the collections of international institutions such as the Metropolitan Museum of Art, New York; the Caldic Collection, Rotterdam; the Kunsthaus Zurich; Sammlung Ludwig, Aachen; the Bern Art Museum; the Solothurn Art Museum; the Bonnefantenmuseum Maastricht; the David Roberts Art Foundation, London; the Musée d’art et d’histoire de la Ville de Neuchâtel, Neuchâtel; the Center PasquART Biel; Museum zu Allerheiligen Schaffhausen as well as the collection of the ZKB Zürcher Kantonalbank and many more.